Background:

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.

Clonality:

monoclonal

Classification:

Primary antibody

Alternative names:

ADLD, lamin B1, LMN, LMN2, LMNB, LMNB1

Specificity:

Human, Mouse, Rat

Host:

Mouse

Isotype:

IgG2a

Immunogen:

lamin B1

Purification:

Protein A+G purification

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

66kd

Form:

liquid

Applications:

ELISA, WB, IF, FC, IP

Recommended dilution:

WB: 1:500-1:2000; IP: 1:5000-1:50000 ; IHC: 1:500-1:2000; IF: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

More info:

Email: info@sobekbio.com

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