Background:

Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Clonality:

monoclonal

Classification:

Primary antibody

Alternative names:

ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C

Specificity:

Human

Host:

Mouse

Isotype:

IgG1

Immunogen:

aldolase C, fructose-bisphosphate

Purification:

Protein A+G purification

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

39 kDa

Form:

liquid

Applications:

ELISA, WB, IF

Recommended dilution:

WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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