anti- TLR4 antibody FNab09837
Background:
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Clonality:
monoclonal
Classification:
Primary antibody
Alternative names:
ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Specificity:
Human, Mouse, Rat
Host:
Mouse
Isotype:
IgG2b
Immunogen:
toll-like receptor 4
Purification:
Protein A+G purification
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
100 kDa
Form:
liquid
Applications:
ELISA, WB, IHC
Recommended dilution:
WB: 1:1000-1:8000; IHC: 1:50-1:500
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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