Background:

CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.

Clonality:

monoclonal

Classification:

Primary antibody

Alternative names:

CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Specificity:

Mouse

Host:

Rat

Isotype:

IgG1

Immunogen:

signaling lymphocytic activation molecule family member 1

Purification:

Protein G purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

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Form:

liquid

Applications:

FC

Recommended dilution:

1：10-1：50

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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