Background:

RAC1b, also named as TC25, belongs to the small GTPase superfamily and Rho family. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, it binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles.

Clonality:

monoclonal

Classification:

Primary antibody

Alternative names:

MIG5, p21 Rac1, RAC1, RAC1b, Ras like protein TC25, TC 25, TC25

Specificity:

Human, Mouse, Rat

Host:

Mouse

Isotype:

IgG1

Immunogen:

ras-related C3 botulinum toxin substrate 1(rho family, small GTP binding protein Rac1)

Purification:

Protein A+G purification

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

21KD

Form:

liquid

Applications:

ELISA, WB,IHC, IP,IF

Recommended dilution:

WB: 1:1000-1:4000; IP: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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