anti- BAX antibody FNab00811
Background:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Clonality:
monoclonal
Classification:
Primary antibody
Alternative names:
BCL2L4
Specificity:
Human, Mouse, Rat
Host:
Mouse
Isotype:
IgG2a
Immunogen:
BCL2-associated X protein
Purification:
Protein A+G purification
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
21 kDa
Form:
liquid
Applications:
ELISA, WB,IHC,IF
Recommended dilution:
WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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