Background:

Angiogenin(ANG), a angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin is also a component of normal human plasma and follicular Xuid. Its widespread expression in human tissues suggests angiogenin may have biological functions in addition to the promotion of angiogenesis. Recently, its biological activity has been extended to stimulating cell proliferation and promoting cell survival. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

ALS9, ANG, Angiogenin, HEL168, Ribonuclease 5, RNase 5, RNASE4, RNASE5

Specificity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

angiogenin, ribonuclease, RNase A family, 5

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

17 kDa

Form:

liquid

Applications:

ELISA, WB, IHC

Recommended dilution:

WB: 1:200-1:2000; IHC: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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