Background:

PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, PRKAA, PRKAA2

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

protein kinase, AMP-activated, alpha 2 catalytic subunit

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

62 kDa

Form:

liquid

Applications:

ELISA, WB, IF, IHC, IP

Recommended dilution:

WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:10-1:100; IP:1:500-1:5000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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