anti- ACVRL1 antibody FNab00131
Background:
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I
Specificity:
Human
Host:
Rabbit
Isotype:
IgG
Immunogen:
activin A receptor type II-like 1
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
56 kDa
Form:
liquid
Applications:
ELISA, WB, IHC, FC, IP
Recommended dilution:
WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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