Alternative names:

FSP;GRO1;GROa;MGSA;MGSA-a;NAP-3;SCYB1

Description:

Recombinant Human CXCL1 with N-terminal human Fc tag

Background:

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

Molecular characterization:

hFc(Glu99-Ala330) CXCL1(Ala35-Asn107)

Molecular weight:

The protein has a predicted molecular mass of 34.0 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CXCL1 is approximately 35-40 kDa due to glycosylation.

Tag:

N-Human Fc Tag

Expression host:

HEK293

Target:

CXCL1

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com