Alternative Name(s):

; Superoxide dismutase [Mn]; mitochondrial; EC 1.15.1.1; Manganese-dependent superoxide dismutase; MnSOD; allergen Alt a MnSOD; Fragment

Species: (Organism)

Alternaria alternata (Alternaria rot fungus) (Torula alternata)

Gene Names:

N/A

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

FNAGGHINHSLFWQNLAPASSNEAK

Expression Region:

1-25aa

Subcellular Location:

Mitochondrion matrix

Tissue Specificity:

Protein Length:

Partial

Pathway:

Mol. Weight:

29.7 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Involvement in disease:

Relevance:

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systs.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Iron/manganese superoxide dismutase family

Reference:

Diagnostic value of Alt a 1, fungal enolase and manganese-dependent superoxide dismutase in the component-resolved diagnosis of allergy to pleosporaceae.Postigo I., Gutierrez-Rodriguez A., Fernandez J., Guisantes J.A., Sunen E., Martinez J.Clin. Exp. Allergy 41:443-451(2011)