Alternative names:

Angiotensin I converting enzyme 2;Severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; HCoV-19; SARS2; 2019-nCoV; COVID-19; COVID-19 virus; Human coronavirus 2019

Host:

Rabbit

Immunogen:

recombinant protein

Reactivity:

COVID-19

Description:

Rabbit IgG,1mg/ml in PBS with 0.02% sodium azide,10% glycerol, pH7.2

Specificity:

ACE2 pAb detects endogenous levels of S-RCD protein.

Bio-MW:

Applications:

WB

Application dilution:

WB: 1:2000~10000

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage & Stability:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background:

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus).

Note:

For research use only, not for use in diagnostic procedure.